The castle was originally built by the Knights of Pythias as an orphanage and senior citizens home for its members and their families in 1913. It was called the Pythian Home of Missouri.
In 1942, the US military acquired the property by "Order of Immediate Possession" for use as offices and service club for recovering injured veterans from WW11. It became part of O'Reilly General Hospital. The military maintained ownership of the property until 1993 when it was sold as "surplus".
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